Associate Data Engineer
Achilles Therapeutics, United Kingdom
Job Description
Achilles Therapeutics is a high growth clinical-stage biopharmaceutical company focused on the development of T cell therapies targeting clonal neoantigens for the treatment of cancer. Originating from pioneering research at Cancer Research UK (CRUK), the Francis Crick Institute and University College London (UCL), we use DNA sequencing data from each patient, together with our proprietary PELEUS bioinformatics platform, to identify clonal neoantigens specific to that patient. From this, we develop personalised T cell therapies and currently have two programs in the clinic for the treatment of Non-Small Cell Lung Cancer and Metastatic Malignant Melanoma.
As a company, we are fast-paced and trailblazing. We are breaking new ground with our science, creating products that have never been made. As no-one has done what we are doing before, there is no playbook to copy. This means we must innovate, adapt and collaborate across our organisation, working together to solve novel problems. This entrepreneurial spirit and approach run through our company and those who thrive here are able to cope with anything that is thrown at them, enjoy ambiguity and thrive on making things happen even when there is not a detailed brief. We work hard and deliver a lot.
This is a unique opportunity to work with a leading team of scientists with an international reputation for excellence in immuno-oncology research and to become a key contributor to the Data Platform team which drives the development of our innovative therapy which is destined to change the course of cancer patient management in the clinic.
Duties/ Responsibilities
- Design, implement, and maintain robust ETL Airflow pipelines.
- Design and implement database schemas that support complex research data while ensuring integrity and security. Collaborate with developers and users to optimize performance and maintain best practices.
- Work closely with scientists to understand their data requirements, proactively identify solutions, and design custom data extracts or visualizations to facilitate their research using both Superset and custom Dash or Shiny apps.
- Identify and streamline repetitive data management tasks by developing scripts and tools that improve efficiency, reduce errors, and free up time for strategic initiatives.
- Collaborate with stakeholders to establish and maintain data quality standards using existing tools and custom ML models.
- Development of dashboards to support the tracking of our clinical studies.
- Support the maintenance of existing data pipelines and support the development of new data pipelines when required.
- Improve data quality through the creation of new data quality checks using great expectations and bespoke scripts.
Requirements
Experience
Required
- Bachelor’s/ Master’s degree in bioinformatics, computer science or equivalent experience.
- 1 year data engineering experience or an equivalent data centric experience.
- Prior experience working with databases or data warehouses.
- Comfortable writing Python and/or SQL code in a version-controlled environment.
- Comfort working in a Linux command-line environment.
Desirable
- Demonstrable experience with processing of biological datasets.
- Experience working and running cloud computing infrastructure e.g., Azure or AWS.
- Experience working with data engineering technologies e.g. Relational Databases, Pandas, Apache Airflow, Apache Superset, Great Expectations, Amazon Glue, AWS Athena, Amazon Textract.
- Experience working with the Atlassian toolchain (Jira, Bitbucket, Confluence).
- Experience working in an Agile/Scrum environment.
Personal requirements
- Good communication skills
- A desire to work in a dynamic fast-paced multidisciplinary team environment.
- An ability to manage multiple, concurrent initiatives.
Benefits
This is a permanent role, offering a competitive benefits package
At Achilles you will enjoy a flexible and dynamic working environment that fosters creativity, leadership, and teamwork. We work hard and deliver a lot
Our benefits package includes a competitive salary and performance related bonus, group pension plan matched up to 6%, life insurance, private medical insurance, and a tax approved all employee share incentive plan.